Prohlížení dle autora "Gahurová, Lenka"
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Age-associated changes of transposable elements activity in the oocytes and differences in their content across mammalian genomes.
Bădici, Marco Constantin (Jihočeská univerzita, 2021)Analysis of expression and DNA methylation of retrotransposons in single oocyte datasets from reproductive young and aged mouse females with the aim to assess the association between aging and altered activity of ... -
Algorithmic prediction of functional changes within protein sequence
Tolar, Nikolas (Jihočeská univerzita, 2021)The Following thesis provides a theoretical background to the biology of a naked mole-rat (Heterocephalus glaber), highlighting its unique characteristics that could potentially be explained by altered epigenetic mechanisms. ... -
Analysis of the expression of transcripts at imprinted loci across mammalian species during early development
Ramirez, Sylvia (Jihočeská univerzita, 2019)To explore the conservation of novel transcripts in imprinted regions identified in mouse and developmental regulation of transcripts in imprinted loci, RNA-seq datasets from six mammalian species from various developmental ... -
Characterization and localization of Tb1290, a putative mitochondrial protein in <i>Trypanosoma brucei</i>
Knobloch, Tomáš (Jihočeská univerzita, 2019)In this thesis methods in-situ tagging, immunofluorescence microscopy, cell fractionation are utilized for localization and RNA interference for determination of essentiality of protein Tb927.11.1290 in Trypanosoma brucei. -
Characterization of oocyte- and embryo-specific 5' untranslated regions (UTRs) of mouse mRNAs
Austenová, Alexandra (Jihočeská univerzita, 2020)To identify, annotate and characterize the oocyte- and embryo-specific 5' UTRs, RNA-seq datasets from various developmental stages of mouse were processed, followed by de novo transcriptome assembly, filtering, and analysis ... -
Charakterizace role genu <i>Fbxw16</i> v myším preimplantačním embryonálním vývoji.
Bláhová, Eliška (Jihočeská univerzita, 2022)V této bakalářské práci se zabývám funkcí neznámého myšího genu Fbxw16 kódujícího F-box proteiny, které jsou součástí ubikvitin-ligázového komplexu. Díky proteolytické degradaci proteinů s mateřským efektem ovlivňuje tento ... -
Identification and characterisation of novel transcripts in mouse oocytes and embryos
Kraváriková, Karolína (Jihočeská univerzita, 2020)The primary goal of this bachelor thesis was to identify novel transcripts in mouse oocytes and preimplantation embryos, analyse their expression profile, protein coding potential, the activity of transposable elements as ... -
Is DNMT<sub>3</sub>L a key factor for de novo DNA methylation in mammalian oocytes?
Behluli, Lirik (Jihočeská univerzita, 2022) -
Molecular mechanisms of predation of planktonic protist <i>Hemistasia phaeocysticola</i>
Knobloch, Tomáš (Jihočeská univerzita, 2021)In this thesis growth curves under specific conditions, fluorescence microscopy, and transcriptomic analyses were used to investigate whether the marine protist Hemistasia phaeocysticola is able to prey on bacteria and ... -
Multispecies analysis of the role of epigenetic factors in aging
Müller, Miriam (Jihočeská univerzita, 2022)The following thesis provides the results of a multispecies analysis that was done to identify expression patterns of 209 genes encoding epigenetic factors that are associated with aging and longevity. The first part of ... -
Novel non-coding transcripts at imprinted loci in mammalian oocytes and embryos
Nenin, Nina (Jihočeská univerzita, 2020)Aims of this thesis were to annotate novel transcripts within clusters of imprinted genes in mouse oocytes and embryo, to analyze expression changes of these transcripts during mouse embryonic development, to identify ... -
Role genu Socs3 v preimplantačním vývoji myších embryí
Tománková, Jana (Jihočeská univerzita, 2020)Gen Socs3 je důležitý pro postimplantační vývoj myších embryí, ale jeho účinek na preimplantační vývoj není znám. Cílem této studie bylo zjistit vliv genu Socs3 na preimplantační vývoj myších embryí, konkrétně na proliferaci ... -
Rypoš lysý a myš domácí jako modelové organismy reprodukčního stárnutí
Kopecká, Eva (Jihočeská univerzita, 2021)The aim of this study is to demonstrate the naked mole rat as a new possible model of reproductive aging. It is also pointing out the reproductive problems and diseases associated with increasing age in women. Furthermore, ... -
Warburg effect in lymph gland of Drosophila melanogaster upon parasitoid wasp infection
Strasser, Paul (Jihočeská univerzita, 2016)Cílem této práce bylo vytvořit ex vivo systém pro měření obsahu laktátu a adenosinu, které jsou produkovány lymfatickými žlázami octomilky Drosophila melanogaster, stanovit rozdíl mezi koncentracemi u larev nenakažených a ...