• A role of Sirt1 in the Notch signalling pathway. 

      Horváth, Matej (Jihočeská univerzita, 2017)
      The aim of this thesis was to examine role of Sirt1 in the Notch signalling pathway, using Drosophila as a model organism. Based on in vivo and in vitro studies, we conclude that Sirt1 plays a positive role in Notch ...
    • The Interplay Between the Notch Signaling Pathway and Cellular Metabolism 

      Slaninová, Věra (Jihočeská univerzita, 2017)
      We identified four metabolic genes as direct targets of Notch signaling pathway both in vitro and in vivo and investigated the hypothesis that Notch directed metabolic changes support the growth of the imaginal wing dics. ...