| dc.contributor.advisor | Jindra, Marek | |
| dc.contributor.author | Smýkal, Vlastimil | |
| dc.date.accessioned | 2021-12-06T12:33:38Z | |
| dc.date.available | 2021-12-06T12:33:38Z | |
| dc.date.issued | 2008 | |
| dc.date.submitted | 2008-04-30 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/23053 | |
| dc.format | 42 s | |
| dc.format | 42 s | |
| dc.language.iso | cze | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.title | Role of Jun and Fos in oogenesis of the beetle <i>Tribolium castaneum</i> | cze |
| dc.title.alternative | Role of Jun and Fos in oogenesis of the beetle <i>Tribolium castaneum</i> | eng |
| dc.type | diplomová práce | cze |
| dc.identifier.stag | 4000 | |
| dc.description.abstract-translated | The aim of this work was to examine the function of the nuclear effectors of JNK signaling, Jun and Fos, in insect telotrophic ovaries, and compare it to the polytrophic ovary of Drosophila. RNA interference knockdown of Jun and Fos in the beetle Tribolium castaneum blocked oogenesis by causing death of follicle cells during growth of the vitellogenic oocytes through caspase-dependent apoptosis. Jun and Fos are therefore required for follicle cell maintenance, which is not the case in Drosophila. Since knockdown of the Jun N-terminal kinase (JNK) had no such effect, Jun and Fos likely act downstream of another kinase during Tribolium oogenesis. We propose that Jun and Fos ensure follicle cell survival upon physical stretching of the follicle epithelium resulting from the oocyte growth. | eng |
| dc.date.accepted | 2008-06-04 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Experimentální biologie - specializace Buněčná a vývojová biologie | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Mgr. | |
| dc.thesis.degree-program | Biologie | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.contributor.referee | Rubsam, Ralph | |
| dc.contributor.referee | Žurovec, Michal | |
