| dc.contributor.advisor | Kotsyfakis, Michalis | |
| dc.contributor.author | Kotál, Jan | |
| dc.date.accessioned | 2021-12-06T14:05:58Z | |
| dc.date.available | 2021-12-06T14:05:58Z | |
| dc.date.issued | 2014 | |
| dc.date.submitted | 2013-12-13 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/24512 | |
| dc.description.abstract | Two cysteine and two serine protease inhibitors from a tick Ixodes ricinus saliva were
overexpressed using a prokaryotic overexpression system and refolded to their native state.
Both cysteine protease inhibitors were tested as potential antigens for an anti-tick vaccine
showing no effect on tick feeding or reproduction. Various immunological methods were
employed to test the potential immunomodulatory function of these proteins without success. | cze |
| dc.format | 94 s; (26910 slov) | |
| dc.format | 94 s; (26910 slov) | |
| dc.language.iso | cze | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.subject | tick | eng |
| dc.subject | ixodes | eng |
| dc.subject | ricinus | eng |
| dc.subject | refolding | eng |
| dc.subject | saliva | eng |
| dc.subject | vaccine | eng |
| dc.title | Production and functional characterization of tick salivary protease inhibitors | cze |
| dc.title.alternative | Production and functional characterization of tick salivary protease inhibitors | eng |
| dc.type | diplomová práce | cze |
| dc.identifier.stag | 28957 | |
| dc.description.abstract-translated | Two cysteine and two serine protease inhibitors from a tick Ixodes ricinus saliva were
overexpressed using a prokaryotic overexpression system and refolded to their native state.
Both cysteine protease inhibitors were tested as potential antigens for an anti-tick vaccine
showing no effect on tick feeding or reproduction. Various immunological methods were
employed to test the potential immunomodulatory function of these proteins without success. | eng |
| dc.date.accepted | 2014-01-21 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Experimentální biologie - specializace Buněčná a vývojová biologie | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Mgr. | |
| dc.thesis.degree-program | Biologie | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.contributor.referee | Sojka, Daniel | |
| dc.contributor.referee | Štěrba, Ján | |
