| dc.contributor.advisor | Ženka, Jan | |
| dc.contributor.author | Auerová, Marie | |
| dc.date.accessioned | 2021-12-06T14:19:14Z | |
| dc.date.available | 2021-12-06T14:19:14Z | |
| dc.date.issued | 2015 | |
| dc.date.submitted | 2014-12-11 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/24764 | |
| dc.format | 82 s. | |
| dc.format | 82 s. | |
| dc.language.iso | cze | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.subject | innate immunity | eng |
| dc.subject | cancer therapy | eng |
| dc.subject | melanoma B16-F10 | eng |
| dc.subject | PAMPs | eng |
| dc.subject | immunodeficiency | eng |
| dc.title | Mechanismy imunitní odpovědi při léčbě rakoviny kotvením ligandů fagocytárních receptorů na povrch nádorových buněk | cze |
| dc.title.alternative | Mechanisms of the immune response during the cancer treatment with ligands of phagocytic receptors anchored to the surface of malignant cells | eng |
| dc.type | diplomová práce | cze |
| dc.identifier.stag | 32530 | |
| dc.description.abstract-translated | The aim of this thesis was to obtain some insights into mechanisms by which the immune system affects melanoma cells after anchoring agonists of phagocytic receptors (laminarin and f-MLF) to their surface. To verify the hypothesis that innate immune system plays a critical role, in vivo experiments were performed on SCID mice. To elucidate the importance of CR3, CD11b-deficient mice were used. In in vitro experiments production of inflammatory cytokines in tumor tissue was examined as well as the release of myeloperoxidase from neutrophil granules after incubation with malignant cells. | eng |
| dc.date.accepted | 2015-01-21 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Klinická biologie | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Mgr. | |
| dc.thesis.degree-program | Biologie | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.contributor.referee | Langhansová, Helena | |
| dc.contributor.referee | Strnádel, Ján | |
