| dc.contributor.advisor | Vonke, Ivan | |
| dc.contributor.author | Štíchová, Zuzana | |
| dc.date.accessioned | 2022-03-08T14:24:12Z | |
| dc.date.available | 2022-03-08T14:24:12Z | |
| dc.date.issued | 2018 | |
| dc.date.submitted | 2017-12-13 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/38608 | |
| dc.format | 88 s. | |
| dc.format | 88 s. | |
| dc.language.iso | cze | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.subject | hyperkoagulační stav | cze |
| dc.subject | trombofilie | cze |
| dc.subject | D-dimery | cze |
| dc.subject | Leidenská mutace | cze |
| dc.subject | tromboembolická nemoc | cze |
| dc.subject | gravidita | cze |
| dc.subject | thrombophilia | eng |
| dc.subject | hypercoagulable states | eng |
| dc.subject | pregnancy | eng |
| dc.subject | D-dimer | eng |
| dc.subject | venous thromboembolism | eng |
| dc.title | Vliv vrozených hyperkoagulačních stavů na hladinu D-d se zaměřením na gravidní ženy | cze |
| dc.title.alternative | The effect of inherited trombophilia on D-dimer concentration in pregnancy | eng |
| dc.type | diplomová práce | cze |
| dc.identifier.stag | 48537 | |
| dc.description.abstract-translated | The thesis analyses the female patients' data from Clinical hematology department in České Budějovice hospital from year 2014 to 2015 and tries to statistically confirm connection between D-dimer level and hypercoagulable states described in previous bachelor thesis. D-dimer assay is due to negative predictive value and high sensitivity an initial laboratory test to rule out tromboembolic disease. However, it has low specificity. The elevated level of D-dimer is observed in conditions like infection, trauma, acute cancer, recent surgery or pregnancy and last studies showed increased D-dimer level even in combination with inherited hypercoagulable states. Thus, it is necessary to analyse the level of D-dimer in pregnant women related to specific hypercoagulable states. Moreover, the thesis analyses the influence of other factors like anticoagulation therapy on D-dimer level and tries to find connection between D-dimer level and pregnancy associated complication, birth weight or a type of delivery. | eng |
| dc.date.accepted | 2018-01-16 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Klinická biologie | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Mgr. | |
| dc.thesis.degree-program | Biologie | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.contributor.referee | Hausdorf, Pavel | |
| dc.contributor.referee | Riegert, Jan | |
