| dc.contributor.advisor | Bruce, Alena | |
| dc.contributor.author | Pekáčová, Aneta | |
| dc.date.accessioned | 2023-03-07T11:04:10Z | |
| dc.date.available | 2023-03-07T11:04:10Z | |
| dc.date.issued | 2019 | |
| dc.date.submitted | 2019-04-17 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/40895 | |
| dc.description.abstract | The aim of my study was to create a Drosophila line lacking the expression of all Sirtuin genes, check its developmental phenotype and characterise its response in stress conditions. The flies had bigger weight than controls, they had decreased fertility and fecundity and they developed more slowly. They showed a trend towards increased resistance to chill coma, but they did not show a significant difference in starvation or oxidative stress assay. Its effect on lifespan is being investigated. | cze |
| dc.format | 70 | |
| dc.format | 70 | |
| dc.language.iso | eng | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.subject | sirtuin | cze |
| dc.subject | drosophila | cze |
| dc.subject | mutation | cze |
| dc.subject | characterisation | cze |
| dc.subject | sirtuin | eng |
| dc.subject | drosophila | eng |
| dc.subject | mutation | eng |
| dc.subject | characterisation | eng |
| dc.title | Characterisation of <i>Drosophila melanogaster</i> mutated for all genes of the Sirtuin family | cze |
| dc.title.alternative | Characterisation of <i>Drosophila melanogaster</i> mutated for all genes of the Sirtuin family | eng |
| dc.type | diplomová práce | cze |
| dc.identifier.stag | 55794 | |
| dc.description.abstract-translated | The aim of my study was to create a Drosophila line lacking the expression of all Sirtuin genes, check its developmental phenotype and characterise its response in stress conditions. The flies had bigger weight than controls, they had decreased fertility and fecundity and they developed more slowly. They showed a trend towards increased resistance to chill coma, but they did not show a significant difference in starvation or oxidative stress assay. Its effect on lifespan is being investigated. | eng |
| dc.date.accepted | 2019-05-22 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Experimentální biologie - specializace Molekulární a buněčná biologie a genetika | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Mgr. | |
| dc.thesis.degree-program | Biologie | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.contributor.referee | Bajgar, Adam | |
| dc.contributor.referee | Kodrík, Dalibor | |
