| dc.contributor.advisor | Kotál, Jan | |
| dc.contributor.author | Pechová, Hana | |
| dc.date.accessioned | 2024-03-12T11:36:27Z | |
| dc.date.available | 2024-03-12T11:36:27Z | |
| dc.date.issued | 2021 | |
| dc.date.submitted | 2020-12-09 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/44860 | |
| dc.description.abstract | The master thesis deals with the analysis of trypsin inhibitor-like cysteine-rich domain-containing peptides (TIL-domain inhibitors) extracted from salivary glands of a tick Ixodes ricinus. It comprises the initial bioinformatical analysis of TIL-domain containing peptide family from I. ricinus, molecular cloning of the representative protein into expression vector, followed by production of recombinant TIL-domain inhibitor in bacteria. A representative TIL-domain gene is proved for their structure, biochemical properties as well as immunomodulatory and anticoagulation features. | cze |
| dc.format | 93 p., 115 123 signs | |
| dc.format | 93 p., 115 123 signs | |
| dc.language.iso | eng | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.subject | trypsin inhibitor-like cysteine-rich domain-containing peptides | cze |
| dc.subject | TIL-domain inhibitors | cze |
| dc.subject | Ixodes ricinus | cze |
| dc.subject | protein expression | cze |
| dc.subject | purification | cze |
| dc.subject | anti-protease activity | cze |
| dc.subject | anticoagulation activity | cze |
| dc.subject | immunomodulation | cze |
| dc.subject | trypsin inhibitor-like cysteine-rich domain-containing peptides | eng |
| dc.subject | TIL-domain inhibitors | eng |
| dc.subject | Ixodes ricinus | eng |
| dc.subject | protein expression | eng |
| dc.subject | purification | eng |
| dc.subject | anti-protease activity | eng |
| dc.subject | anticoagulation activity | eng |
| dc.subject | immunomodulation | eng |
| dc.title | Analysis of trypsin inhibitor-like cysteine-rich domain-containing peptides (TIL-domain inhibitors) from the tick Ixodes ricinus | cze |
| dc.title.alternative | Analysis of trypsin inhibitor-like cysteine-rich domain-containing peptides (TIL-domain inhibitors) from the tick Ixodes ricinus | eng |
| dc.type | diplomová práce | cze |
| dc.identifier.stag | 55941 | |
| dc.description.abstract-translated | The master thesis deals with the analysis of trypsin inhibitor-like cysteine-rich domain-containing peptides (TIL-domain inhibitors) extracted from salivary glands of a tick Ixodes ricinus. It comprises the initial bioinformatical analysis of TIL-domain containing peptide family from I. ricinus, molecular cloning of the representative protein into expression vector, followed by production of recombinant TIL-domain inhibitor in bacteria. A representative TIL-domain gene is proved for their structure, biochemical properties as well as immunomodulatory and anticoagulation features. | eng |
| dc.date.accepted | 2021-01-28 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Biological chemistry | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Mgr. | |
| dc.thesis.degree-program | Biochemistry | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.contributor.referee | Franta, Zdeněk | |
| dc.contributor.referee | Perner, Jan | |
