| dc.contributor.advisor | Franta, Zdeněk | |
| dc.contributor.author | Vejvodová, Kateřina | |
| dc.date.accessioned | 2024-03-12T11:36:52Z | |
| dc.date.available | 2024-03-12T11:36:52Z | |
| dc.date.issued | 2021 | |
| dc.date.submitted | 2021-04-30 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/44883 | |
| dc.format | 74 s. | |
| dc.format | 74 s. | |
| dc.language.iso | eng | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.subject | Flavivirus | eng |
| dc.subject | nonstructural protein NS3 | eng |
| dc.subject | Tick-borne encephalitis virus | eng |
| dc.title | Recombinant production and characterization of protease domain from TBEV nonstructural protein NS3 | cze |
| dc.title.alternative | Recombinant production and characterization of protease domain from TBEV nonstructural protein NS3 | eng |
| dc.type | diplomová práce | cze |
| dc.identifier.stag | 59200 | |
| dc.description.abstract-translated | The aim of this thesis was to produce and characterize recombinant protease domain of
TBEV nonstructural protein 3 (NS3). The NS3 protein of TBEV is essential in viral
replication and plays an indispensable role in cleaving viral polyprotein into structural and nonstructural viral proteins, thus making it an attractive target for antiviral treatment. This thesis summarized the cloning of TBEV NS3 protease,production and purification of recombinant enzyme, biochemical and kinetic characterazion of the protease domain from TBEV NS3. | eng |
| dc.date.accepted | 2021-05-25 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Klinická biologie | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Mgr. | |
| dc.thesis.degree-program | Biologie | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.contributor.referee | Chmelař, Jindřich | |
| dc.contributor.referee | Šíma, Radek | |
