Characterization of TbPH1, a kinetoplastid-specific pleckstrin homology domain containing kinesin-like protein

Abstract

The aim of this master thesis was the investigation of the uncharacterized protein TbPH1, by in silico studies, determining effects of its knock-down, studying the effect of a knock-down on the cell cycle, examining its cellular localization, and finding out about possible complexes and interaction-partners.