The role of Ervl in the mitochondrial import machinery and iron sulphur cluster export machinery in <i>Trypanosoma brucei</i>

Abstract

The aim of this thesis was to determine the subcellular localization of Erv1 and to verify its involvement in the cytosolic iron sulphur cluster assembly. Additionally a search for potential interaction partners was conducted, which could possibly assist Erv1 in the processes where it was suggested to take a part, so either in the biogenesis of iron-sulphur cluster proteins or in the mitochondrial protein import, in procyclic T. brucei.