Elucidating the subunit composition of tRNA-guanine transglycosylase in <i>Trypanosoma brucei</i>
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Jihočeská univerzita
Abstract
The aim of this thesis was to elucidate the relationship and/or interaction between two tRNA-guanine transglycosylase paralogs (putative subunits of the TGT enzyme) identified in Trypanosoma brucei. The overexpression of these proteins was tested in a rescue experiment in a Schizosaccharomyces pombe experimental system.