| dc.contributor.advisor | Doležal, Tomáš | |
| dc.contributor.author | Kubala, Eugen | |
| dc.date.accessioned | 2021-12-06T13:07:59Z | |
| dc.date.available | 2021-12-06T13:07:59Z | |
| dc.date.issued | 2010 | |
| dc.date.submitted | 2010-05-24 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/23382 | |
| dc.description.abstract | Ve vzorcích nádoru prsu bylo nalezeno několik somatických mutací genu Casein kinase I epsilon. Vzhledem k tomu, že genom Drosophily obsahuje homolog tohoto genu - discs overgrown locus, který, pokud je mutován, vede k hyperplastickému přemnožení imaginalních disků křídla - snažil jsem se získat jedince, který by nesl jednu z pozorovaných mutací CKI? ve svém genomu. | cze |
| dc.format | 30 | |
| dc.format | 30 | |
| dc.language.iso | eng | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.title | Study of the Role of mutations L39Q, L49Q, and N78T of Casein Kinase I epsilon in Breast Cancer Using <i>Drosophila Melanogaster</i> as a Model Organism | cze |
| dc.title.alternative | Study of the Role of mutations L39Q, L49Q, and N78T of Casein Kinase I epsilon in Breast Cancer Using <i>Drosophila Melanogaster</i> as a Model Organism | eng |
| dc.type | bakalářská práce | cze |
| dc.identifier.stag | 20450 | |
| dc.description.abstract-translated | Several somatic mutations were found in human gene encoding Casein kinase I epsilon in breast cancer tissue samples. Since there is a homologue in Drosophila genome, discs overgrown locus that leads when mutated to hyperplastic overgrowth of imaginal wing discs, I attempted to obtain a Drosophila, which would carry one of the observed mutations in its genome. | eng |
| dc.date.accepted | 2010-06-21 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Biological Chemistry | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Bc. | |
| dc.thesis.degree-program | Biochemistry | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.contributor.referee | Bruce, Alena | |
