| dc.contributor.advisor | Lukeš, Julius | |
| dc.contributor.author | Haindrich, Alexander Christoph | |
| dc.date.accessioned | 2021-12-06T14:01:47Z | |
| dc.date.available | 2021-12-06T14:01:47Z | |
| dc.date.issued | 2013 | |
| dc.date.submitted | 2013-05-17 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/24188 | |
| dc.description.abstract | In this thesis we investigated genes of the Cytosolic Iron sulfur cluster assembly (CIA) pathway in T. brucei procyclic and blood-stream form for their possible functional redundancy. For this, RNAi double knockdown plasmids were generated containing knockdown partners which were selected based on the proposed model of the CIA pathway in S. cerevisiae. The generated plasmids were transfected into T. brucei cells, and growth effects on the transfectants upon tetracycline induced RNAi was measured. | cze |
| dc.language.iso | eng | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.subject | Iron Sulfur Cluster | cze |
| dc.subject | CIA | cze |
| dc.subject | RNAi | cze |
| dc.subject | Trypanosoma brucei | cze |
| dc.subject | Iron Sulfur Cluster | eng |
| dc.subject | CIA | eng |
| dc.subject | RNAi | eng |
| dc.subject | Trypanosoma brucei | eng |
| dc.title | Iron-Sulfur Cluster Assembly in Trypanosoma brucei | cze |
| dc.title.alternative | Iron-Sulfur Cluster Assembly in Trypanosoma brucei | eng |
| dc.type | bakalářská práce | cze |
| dc.identifier.stag | 27471 | |
| dc.description.abstract-translated | In this thesis we investigated genes of the Cytosolic Iron sulfur cluster assembly (CIA) pathway in T. brucei procyclic and blood-stream form for their possible functional redundancy. For this, RNAi double knockdown plasmids were generated containing knockdown partners which were selected based on the proposed model of the CIA pathway in S. cerevisiae. The generated plasmids were transfected into T. brucei cells, and growth effects on the transfectants upon tetracycline induced RNAi was measured. | eng |
| dc.date.accepted | 2013-06-19 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Biological Chemistry | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Bc. | |
| dc.thesis.degree-program | Biochemistry | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.contributor.referee | Gahura, Ondřej | |
