The role of adenosine receptor in self-activation in immune cells
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Authors
Kopicová, Klára
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Volume Title
Publisher
Jihočeská univerzita
Abstract
Adenosine receptor plays very important role in regulation of immune response. Its
signalling may lead to initiation of metabolic switch, which suppresses energy consumption by peripheral tissues (selfish behaviour of immunes system). In this thesis I attempt to test the potential role of adenosine signalling in self-activation of immune cells which could alternatively explain its role in systemic energetic switch in model organism Drosophila melanogaster.
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Keywords
Extracellular adenosine (e-Ado), adenosine receptor (AdoR), systemic metabolic
switch, self-activation of immune cells, Drosophila melanogaster, Leptopilina boulardi, mutant (homozygous, heterozygous) clones, mitotic recombination., Extracellular adenosine (e-Ado), adenosine receptor (AdoR), systemic metabolic
switch, self-activation of immune cells, Drosophila melanogaster, Leptopilina boulardi, mutant (homozygous, heterozygous) clones, mitotic recombination.