dc.contributor.advisor | Prudnikova, Taťána | |
dc.contributor.author | Guger, Isabella | |
dc.date.accessioned | 2023-03-07T11:02:24Z | |
dc.date.available | 2023-03-07T11:02:24Z | |
dc.date.issued | 2019 | |
dc.date.submitted | 2019-05-09 | |
dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/40725 | |
dc.description.abstract | The aim of this study was to learn the basic and advanced crystallization techniques on the model protein Lysozyme, to crystalize the monotopic integral membrane protein human oxidosqualene cyclase hOSC-WT and its mutant variant hOSC-580W and to optimize the initial crystallization experiments. Moreover, the 3D hOSC protein structure was modelled and compared with already known structure of oxidosqualene cyclase. | cze |
dc.format | 47p | |
dc.format | 47p | |
dc.language.iso | eng | |
dc.publisher | Jihočeská univerzita | cze |
dc.rights | Bez omezení | |
dc.title | Crystallization and modelling studies of human oxydosqualene cyclase hOSC wild type and 580W mutant variant | cze |
dc.title.alternative | Crystallization and modelling studies of human oxydosqualene cyclase hOSC wild type and 580W mutant variant | eng |
dc.type | bakalářská práce | cze |
dc.identifier.stag | 49541 | |
dc.description.abstract-translated | The aim of this study was to learn the basic and advanced crystallization techniques on the model protein Lysozyme, to crystalize the monotopic integral membrane protein human oxidosqualene cyclase hOSC-WT and its mutant variant hOSC-580W and to optimize the initial crystallization experiments. Moreover, the 3D hOSC protein structure was modelled and compared with already known structure of oxidosqualene cyclase. | eng |
dc.date.accepted | 2019-06-17 | |
dc.description.department | Přírodovědecká fakulta | cze |
dc.thesis.degree-discipline | Biological Chemistry | cze |
dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
dc.thesis.degree-name | Bc. | |
dc.thesis.degree-program | Biochemistry | cze |
dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
dc.contributor.referee | Grinkevich, Pavel | |