dc.contributor.advisor | Rudenko, Nataliia | |
dc.contributor.author | Ramzy, Ida | |
dc.date.accessioned | 2024-03-12T08:11:57Z | |
dc.date.available | 2024-03-12T08:11:57Z | |
dc.date.issued | 2020 | |
dc.date.submitted | 2019-12-11 | |
dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/42697 | |
dc.description.abstract | Antibiotic treatment of Lyme disease is a challenging procedure with unexpected outcomes that may arise sometime. According to standard protocols recommended by the Centers for Disease Control and Prevention, USA (CDC) for early Lyme disease, a short course of oral antibiotics cures the majority of cases. This thesis deals with the analysis of the efficiency of 2 majorly used antibiotics, doxycycline and amoxicillin, in elimination of Borrelia infection on laboratory mice model after 2 weeks of treatment. Our results confirmed the presence of persistent forms of spirochetes in mice tissues after antibiotic treatment using the spirochete cultivation method in liquid MKP medium. | cze |
dc.format | 47 | |
dc.format | 47 | |
dc.language.iso | eng | |
dc.publisher | Jihočeská univerzita | cze |
dc.rights | Bez omezení | |
dc.subject | Lyme disease | cze |
dc.subject | Borrelia burgdorferi | cze |
dc.subject | doxycycline | cze |
dc.subject | amoxicillin | cze |
dc.subject | spirochetes | cze |
dc.subject | parasitology | cze |
dc.subject | chronic Lyme disease | cze |
dc.subject | Lyme disease | eng |
dc.subject | Borrelia burgdorferi | eng |
dc.subject | doxycycline | eng |
dc.subject | amoxicillin | eng |
dc.subject | spirochetes | eng |
dc.subject | parasitology | eng |
dc.subject | chronic Lyme disease | eng |
dc.subject | antibiotics | eng |
dc.title | Detection of persistent forms of Borrelia burgdorferi sensu stricto in infected mice after antibiotic treatment | cze |
dc.title.alternative | Detection of persistent forms of Borrelia burgdorferi sensu stricto in infected mice after antibiotic treatment | eng |
dc.type | bakalářská práce | cze |
dc.identifier.stag | 53043 | |
dc.description.abstract-translated | Antibiotic treatment of Lyme disease is a challenging procedure with unexpected outcomes that may arise sometime. According to standard protocols recommended by the Centers for Disease Control and Prevention, USA (CDC) for early Lyme disease, a short course of oral antibiotics cures the majority of cases. This thesis deals with the analysis of the efficiency of 2 majorly used antibiotics, doxycycline and amoxicillin, in elimination of Borrelia infection on laboratory mice model after 2 weeks of treatment. Our results confirmed the presence of persistent forms of spirochetes in mice tissues after antibiotic treatment using the spirochete cultivation method in liquid MKP medium. | eng |
dc.date.accepted | 2020-02-03 | |
dc.description.department | Přírodovědecká fakulta | cze |
dc.thesis.degree-discipline | Biological Chemistry | cze |
dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
dc.thesis.degree-name | Bc. | |
dc.thesis.degree-program | Biochemistry | cze |
dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
dc.contributor.referee | Žákovská, Alena | |