| dc.contributor.advisor | Rudenko, Nataliia | |
| dc.contributor.author | Kapurani, Helena | |
| dc.date.accessioned | 2025-03-06T08:05:34Z | |
| dc.date.available | 2025-03-06T08:05:34Z | |
| dc.date.issued | 2022 | |
| dc.date.submitted | 2021-12-15 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/46137 | |
| dc.description.abstract | Lyme borreliosis is a disease caused by infection of selected members of the Borrelia burgdorferi sensu lato complex, a genus that keeps growing. With time, more and more members of this complex were identified as pathogenic for humans. This work aims to detect the spectrum of Borrelia spirochetes present in samples of Czech patients diagnosed with Lyme disease. Analysis will be used to suggest a tendency between the presence of the spirochetes' DNA found and the diagnosis of the patients. | cze |
| dc.format | 46p. (81,219 characters) | |
| dc.format | 46p. (81,219 characters) | |
| dc.language.iso | eng | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.subject | Lyme borreliosis | cze |
| dc.subject | B. burgdorferi | cze |
| dc.subject | B. miyamotoi | cze |
| dc.subject | infection | cze |
| dc.subject | Czech Republic | cze |
| dc.subject | patients | cze |
| dc.subject | Lyme borreliosis | eng |
| dc.subject | B. burgdorferi | eng |
| dc.subject | B. miyamotoi | eng |
| dc.subject | infection | eng |
| dc.subject | Czech Republic | eng |
| dc.subject | patients | eng |
| dc.title | Detection of Lyme disease spirochetes and Borrelia miyamotoi in samples of Czech patients | cze |
| dc.title.alternative | Detection of Lyme disease spirochetes and Borrelia miyamotoi in samples of Czech patients | eng |
| dc.type | bakalářská práce | cze |
| dc.identifier.stag | 59270 | |
| dc.description.abstract-translated | Lyme borreliosis is a disease caused by infection of selected members of the Borrelia burgdorferi sensu lato complex, a genus that keeps growing. With time, more and more members of this complex were identified as pathogenic for humans. This work aims to detect the spectrum of Borrelia spirochetes present in samples of Czech patients diagnosed with Lyme disease. Analysis will be used to suggest a tendency between the presence of the spirochetes' DNA found and the diagnosis of the patients. | eng |
| dc.date.accepted | 2022-01-24 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Biological Chemistry | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Bc. | |
| dc.thesis.degree-program | Biochemistry | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.contributor.referee | Lloyd, Vett | |
| dc.description.defence | <ul>
<li>Defence was hybrid, the student was present in person, the members of the commission were present in person or connected via MS Teams.</li>
<li>Prof. Grubhoffer welcomed the student and the commission.</li>
<li>The student presented her work „Detection of Lyme disease spirochetes and <em>Borrelia miyamotoi</em> in samples of Czech patients.“, - introduction to the topic, methods, results and summary.</li>
<li>Supervisor Dr. Rudenko presented her review.</li>
<li>Dr. Štěrba presented prof. Lloyd´s opponent review.</li>
<li>Student answered opponent´s questions on why Bbss is considered to have primarily arthritic symptoms, gender differences in Bbss infections in the US and Europe in the studied samples, why the studied samples were classified as problematic, why the presence of human DNA is problematic in the samples, primer specificity.</li>
<li>Student answered questions of the members of the commission:</li>
</ul>
<p>Dr. Rego – how many patient samples for brain analysis, how many positive samples</p>
<p>Dr. Štěrba – the production of the samples</p>
<p> </p>
<p> </p>
<p>3x excellent, 1x very good – excellent</p> | cze |
