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dc.contributor.advisorRego, Ryan Oliver Marino
dc.contributor.authorPaktan, Aylin
dc.date.accessioned2025-03-06T08:05:40Z
dc.date.available2025-03-06T08:05:40Z
dc.date.issued2022
dc.date.submitted2021-12-15
dc.identifier.urihttps://dspace.jcu.cz/handle/20.500.14390/46159
dc.description.abstractThe aim of this thesis was to investigate the interaction of the salivary gland protein, Salp15, in relation to the outer surface protein C, OspC, using in silico analysis, as well as trying to amplify Salp15 from different tick species found in same geographical areas and observing the growth of Borrelia in the midgut and salivary glands of these different tick species in vitro.cze
dc.format39 p. (11463 characters)
dc.format39 p. (11463 characters)
dc.language.isoeng
dc.publisherJihočeská univerzitacze
dc.rightsBez omezení
dc.subjectLyme diseasecze
dc.subjectBorreliacze
dc.subjectIxodescze
dc.subjectDermacentorcze
dc.subjectSalivary glandscze
dc.subjectMidgutcze
dc.subjectSalp15cze
dc.subjectOspCcze
dc.subjectLyme diseaseeng
dc.subjectBorreliaeng
dc.subjectIxodeseng
dc.subjectDermacentoreng
dc.subjectSalivary glandseng
dc.subjectMidguteng
dc.subjectSalp15eng
dc.subjectOspCeng
dc.titleThe Interaction of Borrelia Outer Surface Proteins with Tick Salivary Proteinscze
dc.title.alternativeThe Interaction of Borrelia Outer Surface Proteins with Tick Salivary Proteinseng
dc.typebakalářská prácecze
dc.identifier.stag62746
dc.description.abstract-translatedThe aim of this thesis was to investigate the interaction of the salivary gland protein, Salp15, in relation to the outer surface protein C, OspC, using in silico analysis, as well as trying to amplify Salp15 from different tick species found in same geographical areas and observing the growth of Borrelia in the midgut and salivary glands of these different tick species in vitro.eng
dc.date.accepted2022-01-24
dc.description.departmentPřírodovědecká fakultacze
dc.thesis.degree-disciplineBiological Chemistrycze
dc.thesis.degree-grantorJihočeská univerzita. Přírodovědecká fakultacze
dc.thesis.degree-nameBc.
dc.thesis.degree-programBiochemistrycze
dc.description.gradeDokončená práce s úspěšnou obhajoboucze
dc.contributor.refereeMahmood, Sazzad
dc.description.defence<ul> <li>Defence was online, the student and the members of the commission were connected via MS Teams.</li> <li>Prof. Grubhoffer welcomed the student and the commission.</li> <li>The student presented her work &bdquo;The interaction of <em>Borrelia</em> Outer surface proteins with tick salivary proteins&ldquo;, introduction to the topic, methods, results and summary.</li> <li>Supervisor Dr. Rego presented his review.</li> <li>Oponnent MSc. Mahmood presented his review.</li> <li>Student answered opponent&acute;s questions: compostion of Borrelia antibiotics in the experiments, reason for using antibiotics, isolation of plasmid DNA &ndash; why white E.coli colonies, degenerate primer, primers for Salp 15, phylogenetic trees of OspC and Salp 15.</li> <li>Opponent presented his comments on the thesis.</li> <li>Student answered questions of the members of the commission:</li> </ul> <p>Prof. Grubhoffer &ndash;</p> <p>Dr. Štěrbová &ndash;</p> <p>Dr. Věchtová &ndash;</p> <p>Dr. Štěrba &ndash; the units of the numbers shown in the presentation</p> <p>&nbsp;</p> <p>3x good, 1x failed = good</p>cze


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