| dc.contributor.advisor | Durante, Ignacio Miguel | |
| dc.contributor.author | Bittner, Jacqueline | |
| dc.date.accessioned | 2025-03-06T08:58:34Z | |
| dc.date.available | 2025-03-06T08:58:34Z | |
| dc.date.issued | 2022 | |
| dc.date.submitted | 2022-05-12 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/46845 | |
| dc.description.abstract | During this thesis the localization of the prioritized proteins Tb927.11.13600, Tb927.11.14570, Tb927.4.840 and Tb927.6.4540 and their connection to the tripartite attachment complex of the protozoan parasite Trypanosoma brucei was examined to verify previous annotations found on the TrypTag database. Additionally, the essentiality of the prioritized proteins was evaluated. | cze |
| dc.format | 51 (82 852 characters) | |
| dc.format | 51 (82 852 characters) | |
| dc.language.iso | eng | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.subject | Trypanosoma brucei | cze |
| dc.subject | tripartite attachment complex | cze |
| dc.subject | mitochondrion | cze |
| dc.subject | putative protein | cze |
| dc.subject | Tryptag | cze |
| dc.subject | parasite | cze |
| dc.subject | protein essentiality | cze |
| dc.subject | protein localization | cze |
| dc.subject | endogenous tagging | cze |
| dc.subject | RNA interference | cze |
| dc.subject | Trypanosoma brucei | eng |
| dc.subject | tripartite attachment complex | eng |
| dc.subject | mitochondrion | eng |
| dc.subject | putative protein | eng |
| dc.subject | Tryptag | eng |
| dc.subject | parasite | eng |
| dc.subject | protein essentiality | eng |
| dc.subject | protein localization | eng |
| dc.subject | endogenous tagging | eng |
| dc.subject | RNA interference | eng |
| dc.title | Validation of mitochondrial localization and essentiality of prioritized proteins assigned to the tripartite attachment complex in the protozoan parasite Trypanosoma brucei | cze |
| dc.title.alternative | Validation of mitochondrial localization and essentiality of prioritized proteins assigned to the tripartite attachment complex in the protozoan parasite Trypanosoma brucei | eng |
| dc.type | bakalářská práce | cze |
| dc.identifier.stag | 59305 | |
| dc.description.abstract-translated | During this thesis the localization of the prioritized proteins Tb927.11.13600, Tb927.11.14570, Tb927.4.840 and Tb927.6.4540 and their connection to the tripartite attachment complex of the protozoan parasite Trypanosoma brucei was examined to verify previous annotations found on the TrypTag database. Additionally, the essentiality of the prioritized proteins was evaluated. | eng |
| dc.date.accepted | 2022-06-15 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Biological Chemistry | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Bc. | |
| dc.thesis.degree-program | Biochemistry | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.description.defence | <p>The student, commission members, and the audience were welcomed by the head of the commission, prof. Grubhoffer. The student described the studied organism and the studied complex, the tripartite attachment complex and its components. Next, the aims and the experimental approach were described, followed by the results, which were thoroughly discussed.</p>
<p>The supervisor, Dr Durante presented his review followed by the opponent, Dr Benz. The student answered all of the opponent's questions to her satisfaction. Next, the student answered questions from the commission on the chosen proteins and checking the effectivity of RNAi by qRT-PCR.</p>
<p> </p>
<p>5x excellent - final excellent.</p>
<p>The commission suggests this work for an Award by the head of the Dept. of Chemistry.</p> | cze |
