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Mechanism of Energy Conversion in ATP Driven Molecular Machines: Development of Single-molecule Techniques for Observation of Conformational Changes in Sec Translocon during Protein Transport

dc.contributor.advisorCrossley, Joel
dc.contributor.authorSulejmani, Edrin
dc.date.accessioned2026-01-06T11:54:09Z
dc.date.available2026-01-06T11:54:09Z
dc.date.issued2023
dc.date.submitted2022-12-15
dc.identifier.urihttps://dspace.jcu.cz/handle/20.500.14390/48486
dc.description.abstractOptimization and application of single-molecule techniques, respectively smFRET ALEX confocal microscopy with epi-fluorescence configuration, for examination of conformational space of the SecA in simulated biological conditions.cze
dc.format32
dc.format32
dc.language.isocze
dc.publisherJihočeská univerzitacze
dc.rightsBez omezení
dc.subjectSecAcze
dc.subjectSecYEG complexcze
dc.subjectconfigurationcze
dc.subject'open' conformationcze
dc.subject'closed' conformationcze
dc.subjectFRETcze
dc.subjectATPcze
dc.subjectPPXDcze
dc.subjectHWDcze
dc.subjectNBD2cze
dc.subjectSecAeng
dc.subjectSecYEG complexeng
dc.subjectconfigurationeng
dc.subject'open' conformationeng
dc.subject'closed' conformationeng
dc.subjectFRETeng
dc.subjectATPeng
dc.subjectPPXDeng
dc.subjectHWDeng
dc.subjectNBD2eng
dc.titleMechanism of Energy Conversion in ATP Driven Molecular Machines: Development of Single-molecule Techniques for Observation of Conformational Changes in Sec Translocon during Protein Transportcze
dc.title.alternativeMechanism of Energy Conversion in ATP Driven Molecular Machines: Development of Single-molecule Techniques for Observation of Conformational Changes in Sec Translocon during Protein Transporteng
dc.title.alternativeMekanizmi i konvertimit energjetik ne makinerite molekulare te asistuara nga ATP: Zhvillimi i teknikave nje-molekulare per observim te ndryshimeve konfiguracionale ne Sec Translokon pergjate transportimit proteinikcze
dc.typebakalářská prácecze
dc.identifier.stag59299
dc.description.abstract-translatedOptimization and application of single-molecule techniques, respectively smFRET ALEX confocal microscopy with epi-fluorescence configuration, for examination of conformational space of the SecA in simulated biological conditions.eng
dc.date.accepted2023-01-23
dc.description.departmentPřírodovědecká fakultacze
dc.thesis.degree-disciplineBiological Chemistrycze
dc.thesis.degree-grantorJihočeská univerzita. Přírodovědecká fakultacze
dc.thesis.degree-nameBc.
dc.thesis.degree-programBiochemistrycze
dc.description.gradeDokončená práce s úspěšnou obhajoboucze
dc.description.defence<p>Prof. Grubhoffer welcome Mr. Sulejmani, members of the commission, and the audience. All members of the commission were present. The student introduced the studied moleculr complex and the methods used in the study such as SM-FRET and FCS. Then, he presented his results and discussed them. Uqestions from the commission followed, where he was not able to answer completely, as part of the results were obtained by the supervisor. The participation of the student on the experiments was specified; this information is partly missing from the bachelor thesis.</p> <p>4x very good, 1x good = good</p>cze


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