| dc.contributor.advisor | Ženka, Jan | |
| dc.contributor.author | Simmer, Isabel | |
| dc.date.accessioned | 2026-01-06T11:54:12Z | |
| dc.date.available | 2026-01-06T11:54:12Z | |
| dc.date.issued | 2023 | |
| dc.date.submitted | 2023-05-11 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/20.500.14390/48498 | |
| dc.description.abstract | The aim of this bachelor thesis is to summarize the current knowledge in the field of T regulatory lymphocytes in cancer research as well as during intratumoral MBTA immunotherapy. In addition, methods to detect and target T regulatory lymphocytes are suggested in order to improve MBTA immunotherapy. | cze |
| dc.format | 65 | |
| dc.format | 65 | |
| dc.language.iso | eng | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.subject | Regulatory T lymphocytes | cze |
| dc.subject | MBTA immunotherapy | cze |
| dc.subject | Tregs detection and elimination | cze |
| dc.subject | Cancer | cze |
| dc.subject | Regulatory T lymphocytes | eng |
| dc.subject | MBTA immunotherapy | eng |
| dc.subject | Tregs detection and elimination | eng |
| dc.subject | Cancer | eng |
| dc.title | T Regulatory Lymphocytes During MBTA Immunotherapy of Pancreatic Adenocarcinoma | cze |
| dc.title.alternative | T Regulatory Lymphocytes During MBTA Immunotherapy of Pancreatic Adenocarcinoma | eng |
| dc.type | bakalářská práce | cze |
| dc.identifier.stag | 63311 | |
| dc.description.abstract-translated | The aim of this bachelor thesis is to summarize the current knowledge in the field of T regulatory lymphocytes in cancer research as well as during intratumoral MBTA immunotherapy. In addition, methods to detect and target T regulatory lymphocytes are suggested in order to improve MBTA immunotherapy. | eng |
| dc.date.accepted | 2023-06-15 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Biological Chemistry | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Bc. | |
| dc.thesis.degree-program | Biological Chemistry | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.contributor.referee | Lieskovská, Jaroslava | |
| dc.description.defence | <p>Prof Grubhoffer welcomed the student and commission members; all the members of the commission were present. The student presented information on cancer, cancer treatment and T Regulatory Lymphocytes.</p>
<p>The supervisor and the opponent presented their reviews. The student answered all the questions of the opponent. Next, the student answered questions from the audience on the development of Tregs in the tumours and from which cells they are developed, (in)effectivity of the therapy in bilateral tumours, the principle of binding of mannan to tumour cells and the way anti-CTLA-4 antibodies suppress Tregs inside the tumour. The student partially answered some questions.</p>
<p> </p>
<p>Votes: 2x 1, 2x 2, 2x 3</p>
<p>Final grade: very good</p>
<p>Points: 90</p> | cze |
